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🧬 基因注释:KCNK4

📝 官方信息

官方名称:potassium two pore domain channel subfamily K member 4

功能摘要:This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.460 · 证据 2 条
  • Tardbp 综合评分: 0.451 · 证据 1 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • PCBP2 综合评分: 0.324 · 证据 1 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • ELAVL3 综合评分: 0.244 · 证据 1 条
  • U2af2 综合评分: 0.224 · 证据 1 条
  • U2af1 综合评分: 0.212 · 证据 1 条
  • NXF1 综合评分: 0.162 · 证据 1 条
  • Rnps1 综合评分: 0.162 · 证据 1 条
  • Srsf7 综合评分: 0.162 · 证据 1 条
  • CPSF6 综合评分: 0.150 · 证据 2 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
  • CSTF2T 综合评分: 0.100 · 证据 2 条
  • Rbm7 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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