🧬 基因注释：KIRREL2
📝 官方信息
官方名称：kirre like nephrin family adhesion molecule 2
功能摘要：This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016].
🎯 作为靶基因的剪接因子
- CPSF1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录