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基因注释:KLK14

官方信息

官方名称:kallikrein related peptidase 14

功能摘要:This gene encodes a member of the kallikrein subfamily of serine proteases that have diverse physiological functions such as regulation of blood pressure and desquamation. The altered expression of this gene is implicated in the progression of different cancers including breast and prostate tumors. The encoded protein is a precursor that is proteolytically processed to generate the functional enzyme. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015].

作为靶基因的剪接因子
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • Rbmx 综合评分: 0.100 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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