🧬 基因注释：KRT80
官方名称：keratin 80
功能摘要：Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
- CSTF2 置信度: 2.0
- CSTF2T 置信度: 2.0
- EIF4A3 置信度: 2.0
- EWSR1 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPK 置信度: 2.0
- MBNL1 置信度: 2.0
- PTBP1 置信度: 2.0
- MSI1 置信度: 1.0
- PCBP2 置信度: 1.0
- Rnps1 置信度: 1.0
- SRSF3 置信度: 1.0
- Sf3b1 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf6 置信度: 1.0
- Srsf7 置信度: 1.0
- TFIP11 置信度: 1.0
- Tra2b 置信度: 1.0
- U2af1 置信度: 1.0
该基因暂无关联疾病记录