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基因注释:KCNAB2

官方信息

官方名称:potassium voltage-gated channel subfamily A regulatory beta subunit 2

功能摘要:Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010].

作为靶基因的剪接因子
  • HNRNPM 综合评分: 0.448 · 证据 2 条
  • HNRNPL 综合评分: 0.398 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • MBNL2 综合评分: 0.324 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Mbnl2 综合评分: 0.262 · 证据 1 条
  • PCBP2 综合评分: 0.262 · 证据 1 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • CELF2 综合评分: 0.212 · 证据 2 条
  • CSTF2 综合评分: 0.212 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
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