SpliceAtlasDB
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🧬 基因注释:LCP1

📝 官方信息

官方名称:lymphocyte cytosolic protein 1

功能摘要:Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPL 综合评分: 0.444 · 证据 2 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • PTBP1 综合评分: 0.362 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • RBM39 综合评分: 0.312 · 证据 2 条
  • CELF2 综合评分: 0.310 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • PCBP2 综合评分: 0.298 · 证据 1 条
  • Tardbp 综合评分: 0.294 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • Srsf1 综合评分: 0.212 · 证据 1 条
  • U2af1 综合评分: 0.212 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • Rbpms 综合评分: 0.162 · 证据 1 条
  • AQR 综合评分: 0.150 · 证据 1 条
  • CPSF6 综合评分: 0.150 · 证据 2 条
🏥 关联疾病

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