🧬 基因注释：LSM5
📝 官方信息
官方名称：LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
功能摘要：Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.474 · 证据 2 条
- FUS 综合评分: 0.424 · 证据 1 条
- PTBP1 综合评分: 0.424 · 证据 2 条
- fus 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPC 综合评分: 0.412 · 证据 2 条
- FUBP1 综合评分: 0.312 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- RBM10 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- CPSF6 综合评分: 0.212 · 证据 2 条
- PABPC4 综合评分: 0.212 · 证据 2 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- TFIP11 综合评分: 0.212 · 证据 1 条
- U2af1 综合评分: 0.212 · 证据 1 条
- MATR3 综合评分: 0.200 · 证据 1 条
- PCBP2 综合评分: 0.200 · 证据 1 条
- PRPF8 综合评分: 0.200 · 证据 1 条
- ELAVL3 综合评分: 0.198 · 证据 1 条
🏥 关联疾病
neurodegenerative disease
中关联 (0.499)
intelligence
低关联 (0.282)
heart failure
低关联 (0.211)
attention deficit hyperactivity disorder
低关联 (0.207)
protozoa infectious disease
低关联 (0.201)
food allergy
低关联 (0.201)
autism spectrum disorder
低关联 (0.200)
insomnia
低关联 (0.200)
schizophrenia
低关联 (0.192)
Abnormality of the skeletal system
低关联 (0.183)