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🧬 基因注释:MAPK7

📝 官方信息

官方名称:mitogen-activated protein kinase 7

功能摘要:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • PCBP2 综合评分: 0.298 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • Rnps1 综合评分: 0.198 · 证据 1 条
  • EIF4A3 综合评分: 0.162 · 证据 2 条
  • Rbmx 综合评分: 0.162 · 证据 1 条
  • YBX1 综合评分: 0.162 · 证据 1 条
  • ACIN1 综合评分: 0.150 · 证据 2 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
  • Srsf1 综合评分: 0.150 · 证据 1 条
  • Srsf2 综合评分: 0.150 · 证据 1 条
  • Srsf3 综合评分: 0.150 · 证据 1 条
  • Srsf4 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

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