🧬 基因注释：MAPT
📝 官方信息
官方名称：microtubule associated protein tau
功能摘要：This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- SRSF1 综合评分: 0.693 · 证据 1 条
- Srsf1 综合评分: 0.693 · 证据 1 条
- FUS 综合评分: 0.357 · 证据 1 条
- Fus 综合评分: 0.357 · 证据 1 条
- fus 综合评分: 0.357 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
- NOVA1 综合评分: 0.324 · 证据 2 条
- SRSF11 综合评分: 0.307 · 证据 1 条
- SRSF4 综合评分: 0.307 · 证据 1 条
- Srsf4 综合评分: 0.307 · 证据 1 条
- TARDBP 综合评分: 0.307 · 证据 1 条
- Tardbp 综合评分: 0.307 · 证据 1 条
- SRSF10 综合评分: 0.300 · 证据 1 条
- SRSF5 综合评分: 0.300 · 证据 1 条
- SRSF7 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Srsf5 综合评分: 0.300 · 证据 1 条
- Srsf7 综合评分: 0.300 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录