🧬 基因注释：MAPT
📝 官方信息
官方名称：microtubule associated protein tau
功能摘要：This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- CSTF2 置信度: 2.0
- HNRNPA0 置信度: 2.0
- HNRNPA1 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPA3 置信度: 2.0
- HNRNPH1 置信度: 2.0
- HNRNPH2 置信度: 2.0
- HNRNPH3 置信度: 2.0
- NOVA1 置信度: 2.0
- RBM15 置信度: 2.0
- RSF1 置信度: 2.0
- SF4 置信度: 2.0
- B52 置信度: 1.0
- FUS 置信度: 1.0
- Fus 置信度: 1.0
- HNRNPA1L2 置信度: 1.0
- HNRNPA1P4 置信度: 1.0
- HNRNPP-FUS-TLS 置信度: 1.0
- Mbnl2 置信度: 1.0
- Nova2 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录