基因注释：MEPE

官方名称：matrix extracellular phosphoglycoprotein

功能摘要：This gene encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking this gene are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].

• U2af1 综合评分: 0.212 · 证据 1 条

该基因暂无关联疾病记录