🧬 基因注释：MICB
📝 官方信息
官方名称：MHC class I polypeptide-related sequence B
功能摘要：This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
🎯 作为靶基因的剪接因子
- RBM15 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录