🧬 基因注释：MMP14
官方名称：matrix metallopeptidase 14
功能摘要：Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008].
- CSTF2T 置信度: 2.0
- HNRNPA2B1 置信度: 2.0
- HNRNPH1 置信度: 2.0
- MBNL1 置信度: 2.0
- RBFOX2 置信度: 2.0
- RBM10 置信度: 2.0
- RBM20 置信度: 2.0
- RBM39 置信度: 2.0
- MSI1 置信度: 1.0
- Mbnl2 置信度: 1.0
- PCBP2 置信度: 1.0
- PRPF4 置信度: 1.0
- PRPF8 置信度: 1.0
- QKI 置信度: 1.0
- Rbmx 置信度: 1.0
- Rbpms 置信度: 1.0
- SRSF3 置信度: 1.0
- Sf3b1 置信度: 1.0
- Srsf1 置信度: 1.0
- Srsf2 置信度: 1.0
该基因暂无关联疾病记录