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🧬 基因注释:MMP15

📝 官方信息

官方名称:matrix metallopeptidase 15

功能摘要:This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein may play a role in cancer progression. [provided by RefSeq, Jan 2016].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.362 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • PCBP1 综合评分: 0.200 · 证据 2 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • SF3A3 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • UPF1 综合评分: 0.162 · 证据 1 条
  • AQR 综合评分: 0.150 · 证据 1 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
  • GRSF1 综合评分: 0.150 · 证据 2 条
  • PRPF4 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • CPSF1 综合评分: 0.100 · 证据 1 条
  • EIF4A3 综合评分: 0.100 · 证据 2 条
  • NXF1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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