🧬 基因注释：MPP1
官方名称：MAGUK p55 scaffold protein 1
功能摘要：This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
- HNRNPC 综合评分: 0.448 · 证据 2 条
- SRSF2 综合评分: 0.424 · 证据 1 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- FUS 综合评分: 0.362 · 证据 1 条
- fus 综合评分: 0.362 · 证据 1 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
- ELAVL3 综合评分: 0.306 · 证据 1 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- Srsf2 综合评分: 0.300 · 证据 1 条
- Mbnl2 综合评分: 0.298 · 证据 1 条
- MATR3 综合评分: 0.262 · 证据 1 条
- PABPC4 综合评分: 0.212 · 证据 2 条
- Srsf1 综合评分: 0.212 · 证据 1 条
- PRPF8 综合评分: 0.200 · 证据 1 条
- U2af2 综合评分: 0.198 · 证据 1 条
该基因暂无关联疾病记录