SpliceAtlasDB
← 返回基因注释查询

🧬 基因注释:MRPL23

📝 官方信息

官方名称:mitochondrial ribosomal protein L23

功能摘要:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPH1 综合评分: 0.474 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPM 综合评分: 0.412 · 证据 2 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • Srsf1 综合评分: 0.212 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • CSTF2T 综合评分: 0.162 · 证据 2 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • GRSF1 综合评分: 0.150 · 证据 2 条
  • PABPC4 综合评分: 0.150 · 证据 2 条
  • PRPF4 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • CPSF3 综合评分: 0.100 · 证据 1 条
  • EIF4A3 综合评分: 0.100 · 证据 2 条
  • HNRNPUL1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接