🧬 基因注释：MYD88
📝 官方信息
官方名称：MYD88 innate immune signal transduction adaptor
功能摘要：This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010].
🎯 作为靶基因的剪接因子
- HNRNPL 综合评分: 0.444 · 证据 2 条
- RBFOX2 综合评分: 0.398 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
- Tardbp 综合评分: 0.274 · 证据 1 条
- Rbmx 综合评分: 0.274 · 证据 1 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- UPF1 综合评分: 0.244 · 证据 1 条
- PCBP2 综合评分: 0.200 · 证据 1 条
- SF3A3 综合评分: 0.200 · 证据 1 条
- RBM20 综合评分: 0.162 · 证据 2 条
- Rbpms 综合评分: 0.162 · 证据 1 条
- AQR 综合评分: 0.150 · 证据 1 条
- TFIP11 综合评分: 0.150 · 证据 1 条
- U2af1 综合评分: 0.150 · 证据 1 条
- NXF1 综合评分: 0.100 · 证据 1 条
- Srsf7 综合评分: 0.100 · 证据 1 条
- U2af2 综合评分: 0.100 · 证据 1 条
- YBX1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录