🧬 基因注释：MTPN

官方名称：myotrophin

功能摘要：The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6.4 kDa tumor antigen that is associated with myeloproliferative disease. [provided by RefSeq, Jul 2008].

• RBFOX2 综合评分: 0.486 · 证据 2 条
• HNRNPC 综合评分: 0.474 · 证据 2 条
• Tardbp 综合评分: 0.454 · 证据 1 条
• HNRNPH1 综合评分: 0.448 · 证据 2 条
• MBNL2 综合评分: 0.442 · 证据 1 条
• FUS 综合评分: 0.424 · 证据 1 条
• fus 综合评分: 0.424 · 证据 1 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• ELAVL3 综合评分: 0.368 · 证据 1 条
• CELF2 综合评分: 0.364 · 证据 2 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• Nova2 综合评分: 0.360 · 证据 1 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPF 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• Mbnl2 综合评分: 0.344 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• FUBP1 综合评分: 0.312 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• HNRNPD 综合评分: 0.300 · 证据 2 条

该基因暂无关联疾病记录