🧬 基因注释:NCBP2
📝 官方信息
官方名称:nuclear cap binding protein subunit 2
功能摘要:The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.524 · 证据 2 条
- RBFOX2 综合评分: 0.514 · 证据 2 条
- FUS 综合评分: 0.460 · 证据 1 条
- fus 综合评分: 0.460 · 证据 1 条
- HNRNPA2B1 综合评分: 0.448 · 证据 2 条
- Tardbp 综合评分: 0.403 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- UPF1 综合评分: 0.322 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- Srsf2 综合评分: 0.300 · 证据 1 条
- Srsf3 综合评分: 0.300 · 证据 1 条
- Srsf1 综合评分: 0.274 · 证据 1 条
- PCBP2 综合评分: 0.262 · 证据 1 条
🏥 关联疾病
HIV infection
中关联 (0.594)
neurodegenerative disease
中关联 (0.537)
acrocephalosyndactyly
低关联 (0.370)
dengue disease
低关联 (0.370)
ulcerative colitis
低关联 (0.363)
Crohn's disease
低关联 (0.204)