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🧬 基因注释:NHP2

📝 官方信息

官方名称:NHP2 ribonucleoprotein

功能摘要:This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.460 · 证据 1 条
  • RBFOX2 综合评分: 0.460 · 证据 2 条
  • fus 综合评分: 0.460 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.398 · 证据 1 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • U2af1 综合评分: 0.324 · 证据 1 条
  • U2af2 综合评分: 0.322 · 证据 1 条
  • RBM10 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • Rbmx 综合评分: 0.286 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • UPF1 综合评分: 0.244 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
  • PCBP2 综合评分: 0.200 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
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