🧬 基因注释：NQO1

官方名称：NAD(P)H quinone dehydrogenase 1

功能摘要：This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.524 · 证据 2 条
• HNRNPA1 综合评分: 0.412 · 证据 2 条
• HNRNPM 综合评分: 0.412 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• SRSF3 综合评分: 0.300 · 证据 1 条
• fus 综合评分: 0.300 · 证据 1 条
• UPF1 综合评分: 0.296 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• U2af2 综合评分: 0.260 · 证据 1 条
• TIA1 综合评分: 0.250 · 证据 1 条
• ELAVL3 综合评分: 0.224 · 证据 1 条
• YBX1 综合评分: 0.224 · 证据 1 条
• TFIP11 综合评分: 0.212 · 证据 1 条
• PCBP2 综合评分: 0.200 · 证据 1 条
• SF3A3 综合评分: 0.200 · 证据 1 条
• Rbm7 综合评分: 0.162 · 证据 1 条

该基因暂无关联疾病记录