基因注释 - NR4A3

📝 官方信息

官方名称：nuclear receptor subfamily 4 group A member 3

功能摘要：This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

🎯 作为靶基因的剪接因子

Rnps1 综合评分: 0.336 · 证据 1 条
HNRNPK 综合评分: 0.300 · 证据 2 条
PTBP1 综合评分: 0.300 · 证据 2 条
MBNL2 综合评分: 0.262 · 证据 1 条
EWSR1 综合评分: 0.250 · 证据 2 条
RBM15 综合评分: 0.250 · 证据 2 条
Tardbp 综合评分: 0.212 · 证据 1 条
Mbnl2 综合评分: 0.200 · 证据 1 条
Nova2 综合评分: 0.200 · 证据 1 条
CPSF4 综合评分: 0.150 · 证据 2 条
CSTF2 综合评分: 0.150 · 证据 2 条
EIF4A3 综合评分: 0.100 · 证据 2 条
Rbm7 综合评分: 0.100 · 证据 1 条
Rbmx 综合评分: 0.100 · 证据 1 条
Rbpms 综合评分: 0.100 · 证据 1 条
U2af2 综合评分: 0.100 · 证据 1 条
UPF1 综合评分: 0.100 · 证据 1 条

🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接

NCBI Gene GenBank Ensembl GeneCards UniProt

🧬 基因注释：NR4A3