🧬 基因注释：NACA

官方名称：nascent polypeptide associated complex subunit alpha

功能摘要：This gene encodes a protein that associates with basic transcription factor 3 (BTF3) to form the nascent polypeptide-associated complex (NAC). This complex binds to nascent proteins that lack a signal peptide motif as they emerge from the ribosome, blocking interaction with the signal recognition particle (SRP) and preventing mistranslocation to the endoplasmic reticulum. This protein is an IgE autoantigen in atopic dermatitis patients. Alternative splicing results in multiple transcript variants, but the full length nature of some of these variants, including those encoding very large proteins, has not been determined. There are multiple pseudogenes of this gene on different chromosomes. [provided by RefSeq, Feb 2016].

• HNRNPC 综合评分: 0.510 · 证据 2 条
• Srsf3 综合评分: 0.444 · 证据 1 条
• RBFOX2 综合评分: 0.424 · 证据 2 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• QKI 综合评分: 0.412 · 证据 1 条
• HNRNPK 综合评分: 0.398 · 证据 2 条
• Tardbp 综合评分: 0.364 · 证据 1 条
• FUS 综合评分: 0.362 · 证据 1 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• fus 综合评分: 0.362 · 证据 1 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPF 综合评分: 0.350 · 证据 2 条
• HNRNPM 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• EWSR1 综合评分: 0.348 · 证据 2 条
• U2af1 综合评分: 0.346 · 证据 1 条
• U2af2 综合评分: 0.336 · 证据 1 条
• PRPF8 综合评分: 0.324 · 证据 1 条
• RBM10 综合评分: 0.312 · 证据 2 条
• RBM15 综合评分: 0.312 · 证据 2 条

该基因暂无关联疾病记录