🧬 基因注释：OXGR1
📝 官方信息
官方名称：oxoglutarate receptor 1
功能摘要：This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016].
🎯 作为靶基因的剪接因子
- HNRNPC 置信度: 2.0
🏥 关联疾病
该基因暂无关联疾病记录