🧬 基因注释：PAK6

官方名称：p21 (RAC1) activated kinase 6

功能摘要：This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015].

• RBFOX2 综合评分: 0.486 · 证据 2 条
• FUS 综合评分: 0.474 · 证据 1 条
• fus 综合评分: 0.474 · 证据 1 条
• HNRNPC 综合评分: 0.412 · 证据 2 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• QKI 综合评分: 0.350 · 证据 1 条
• FUBP1 综合评分: 0.348 · 证据 2 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• RBM10 综合评分: 0.312 · 证据 2 条
• KHSRP 综合评分: 0.300 · 证据 2 条
• PTBP1 综合评分: 0.300 · 证据 2 条
• PCBP2 综合评分: 0.298 · 证据 1 条
• CPSF6 综合评分: 0.274 · 证据 2 条
• CSTF2 综合评分: 0.274 · 证据 2 条
• U2af2 综合评分: 0.274 · 证据 1 条
• PRPF8 综合评分: 0.262 · 证据 1 条
• RBM15 综合评分: 0.250 · 证据 2 条
• U2af1 综合评分: 0.212 · 证据 1 条
• Rnps1 综合评分: 0.198 · 证据 1 条

该基因暂无关联疾病记录