🧬 基因注释：PCDH11X
官方名称：protocadherin 11 X-linked
功能摘要：This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014].
- HNRNPC 综合评分: 0.448 · 证据 2 条
- PTBP1 综合评分: 0.398 · 证据 2 条
- Srsf3 综合评分: 0.362 · 证据 1 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- RBM10 综合评分: 0.312 · 证据 2 条
- FUS 综合评分: 0.300 · 证据 1 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
- SRSF3 综合评分: 0.300 · 证据 1 条
- SRSF9 综合评分: 0.300 · 证据 1 条
- fus 综合评分: 0.300 · 证据 1 条
- Rnps1 综合评分: 0.286 · 证据 1 条
- U2af1 综合评分: 0.274 · 证据 1 条
- Nova2 综合评分: 0.262 · 证据 1 条
- SF3A3 综合评分: 0.262 · 证据 1 条
- CPSF7 综合评分: 0.248 · 证据 2 条
- ELAVL3 综合评分: 0.244 · 证据 1 条
- CPSF6 综合评分: 0.212 · 证据 2 条
该基因暂无关联疾病记录