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🧬 基因注释:PDE1B

📝 官方信息

官方名称:phosphodiesterase 1B

功能摘要:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].

🎯 作为靶基因的剪接因子
  • CELF2 综合评分: 0.274 · 证据 2 条
  • U2af2 综合评分: 0.224 · 证据 1 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • Srsf4 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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