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🧬 基因注释:PEBP1

📝 官方信息

官方名称:phosphatidylethanolamine binding protein 1

功能摘要:This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome. [provided by RefSeq, Jul 2015].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.496 · 证据 2 条
  • HNRNPA1 综合评分: 0.412 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPH1 综合评分: 0.412 · 证据 2 条
  • FUS 综合评分: 0.362 · 证据 1 条
  • fus 综合评分: 0.362 · 证据 1 条
  • ELAVL3 综合评分: 0.353 · 证据 1 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • MBNL2 综合评分: 0.324 · 证据 1 条
  • EWSR1 综合评分: 0.312 · 证据 2 条
  • FUBP1 综合评分: 0.312 · 证据 2 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • Srsf3 综合评分: 0.300 · 证据 1 条
  • PRPF8 综合评分: 0.298 · 证据 1 条
  • GRSF1 综合评分: 0.274 · 证据 2 条
  • Rbmx 综合评分: 0.274 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

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