🧬 基因注释：PFDN5
📝 官方信息
官方名称：prefoldin subunit 5
功能摘要：This gene encodes a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- RBFOX2 综合评分: 0.514 · 证据 2 条
- FUS 综合评分: 0.460 · 证据 1 条
- fus 综合评分: 0.460 · 证据 1 条
- HNRNPC 综合评分: 0.448 · 证据 2 条
- PTBP1 综合评分: 0.444 · 证据 2 条
- Tardbp 综合评分: 0.356 · 证据 1 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- U2af2 综合评分: 0.336 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- SRSF2 综合评分: 0.300 · 证据 1 条
- Srsf2 综合评分: 0.300 · 证据 1 条
- GRSF1 综合评分: 0.274 · 证据 2 条
- PRPF8 综合评分: 0.262 · 证据 1 条
- Rbmx 综合评分: 0.260 · 证据 1 条
- EWSR1 综合评分: 0.250 · 证据 2 条
- RBM15 综合评分: 0.250 · 证据 2 条
- RBM39 综合评分: 0.250 · 证据 2 条
- TIA1 综合评分: 0.250 · 证据 1 条
- CELF2 综合评分: 0.248 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录