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🧬 基因注释:PILRB

📝 官方信息

官方名称:paired immunoglobin like type 2 receptor beta

功能摘要:The paired immunoglobin-like type 2 receptors consist of highly related activating and inhibitory receptors that are involved in the regulation of many aspects of the immune system. The paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. This gene encodes the activating member of the receptor pair and contains a truncated cytoplasmic tail relative to its inhibitory counterpart (PILRA), that has a long cytoplasmic tail with immunoreceptor tyrosine-based inhibitory (ITIM) motifs. This gene is thought to have arisen from a duplication of the inhibitory PILRA gene and evolved to acquire its activating function. [provided by RefSeq, Jun 2013].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.474 · 证据 2 条
  • HNRNPK 综合评分: 0.444 · 证据 2 条
  • HNRNPU 综合评分: 0.398 · 证据 2 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • TIA1 综合评分: 0.312 · 证据 1 条
  • U2af1 综合评分: 0.310 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF2 综合评分: 0.300 · 证据 1 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Rnps1 综合评分: 0.286 · 证据 1 条
  • Srsf1 综合评分: 0.274 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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