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🧬 基因注释:PLCB2

📝 官方信息

官方名称:phospholipase C beta 2

功能摘要:The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017].

🎯 作为靶基因的剪接因子
  • SRSF2 综合评分: 0.362 · 证据 1 条
  • Tardbp 综合评分: 0.310 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • RBM39 综合评分: 0.250 · 证据 2 条
  • U2af2 综合评分: 0.244 · 证据 1 条
  • PRPF8 综合评分: 0.200 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
  • CSTF2T 综合评分: 0.100 · 证据 2 条
  • EIF4A3 综合评分: 0.100 · 证据 2 条
  • NXF1 综合评分: 0.100 · 证据 1 条
🏥 关联疾病

该基因暂无关联疾病记录

🔗 外部数据库链接