🧬 基因注释：POLR2J2

官方名称：RNA polymerase II subunit J2

功能摘要：This gene is a member of the RNA polymerase II subunit 11 gene family, which includes three genes in a cluster on chromosome 7q22.1 and a pseudogene on chromosome 7p13. The founding member of this family, DNA directed RNA polymerase II polypeptide J, has been shown to encode a subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This locus produces multiple, alternatively spliced transcripts that potentially express isoforms with distinct C-termini compared to DNA directed RNA polymerase II polypeptide J. Most or all variants are spliced to include additional non-coding exons at the 3' end which makes them candidates for nonsense-mediated decay (NMD). Consequently, it is not known if this locus expresses a protein or proteins in vivo. [provided by RefSeq, Jul 2008].

• HNRNPC 综合评分: 0.474 · 证据 2 条
• RBFOX2 综合评分: 0.460 · 证据 2 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• HNRNPA2B1 综合评分: 0.350 · 证据 2 条
• PRPF8 综合评分: 0.324 · 证据 1 条
• RBM10 综合评分: 0.312 · 证据 2 条
• FUS 综合评分: 0.300 · 证据 1 条
• fus 综合评分: 0.300 · 证据 1 条
• Srsf1 综合评分: 0.294 · 证据 1 条
• RBM15 综合评分: 0.250 · 证据 2 条
• AQR 综合评分: 0.212 · 证据 1 条
• CPSF6 综合评分: 0.212 · 证据 2 条
• CPSF1 综合评分: 0.162 · 证据 1 条
• SAFB2 综合评分: 0.162 · 证据 1 条
• U2af2 综合评分: 0.162 · 证据 1 条
• CPSF7 综合评分: 0.150 · 证据 2 条
• Tardbp 综合评分: 0.150 · 证据 1 条
• U2af1 综合评分: 0.150 · 证据 1 条
• CSTF2T 综合评分: 0.100 · 证据 2 条
• Rbm7 综合评分: 0.100 · 证据 1 条

该基因暂无关联疾病记录