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基因注释:PPBP

官方信息

官方名称:pro-platelet basic protein

功能摘要:The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014].

作为靶基因的剪接因子
  • U2af2 综合评分: 0.198 · 证据 1 条
  • U2af1 综合评分: 0.150 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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