🧬 基因注释:PPM1G
📝 官方信息
官方名称:protein phosphatase, Mg2+/Mn2+ dependent 1G
功能摘要:The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.564 · 证据 2 条
- FUS 综合评分: 0.496 · 证据 1 条
- fus 综合评分: 0.496 · 证据 1 条
- SRSF9 综合评分: 0.424 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPH1 综合评分: 0.412 · 证据 2 条
- SRSF2 综合评分: 0.398 · 证据 1 条
- Srsf3 综合评分: 0.398 · 证据 1 条
- TIA1 综合评分: 0.374 · 证据 1 条
- Tardbp 综合评分: 0.372 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- Rnps1 综合评分: 0.314 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
- HNRNPK 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
- PTBP1 综合评分: 0.300 · 证据 2 条
- RBFOX2 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录