🧬 基因注释：PRAME
📝 官方信息
官方名称：PRAME nuclear receptor transcriptional regulator
功能摘要：This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014].
🎯 作为靶基因的剪接因子
- CPSF6 置信度: 2.0
- CSTF2T 置信度: 2.0
- EIF4A3 置信度: 2.0
- HNRNPA1 置信度: 2.0
- HNRNPK 置信度: 2.0
- HNRNPL 置信度: 2.0
- HNRNPM 置信度: 2.0
- HNRNPU 置信度: 2.0
- PABPC4 置信度: 2.0
- PCBP1 置信度: 2.0
- PTBP1 置信度: 2.0
- RBM22 置信度: 2.0
- AQR 置信度: 1.0
- FUS 置信度: 1.0
- LUC7L2 置信度: 1.0
- MATR3 置信度: 1.0
- PRPF8 置信度: 1.0
- SAFB 置信度: 1.0
- SRSF2 置信度: 1.0
- Srsf1 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录