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🧬 基因注释:PRDX2

📝 官方信息

官方名称:peroxiredoxin 2

功能摘要:This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.486 · 证据 2 条
  • Tardbp 综合评分: 0.480 · 证据 1 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • PCBP2 综合评分: 0.360 · 证据 1 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • EWSR1 综合评分: 0.348 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • SRSF9 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • U2af1 综合评分: 0.274 · 证据 1 条
  • Rbmx 综合评分: 0.274 · 证据 1 条
  • UPF1 综合评分: 0.274 · 证据 1 条
  • PCBP1 综合评分: 0.262 · 证据 2 条
  • YBX1 综合评分: 0.260 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • Rnps1 综合评分: 0.224 · 证据 1 条
  • CPSF6 综合评分: 0.212 · 证据 2 条
🏥 关联疾病

该基因暂无关联疾病记录

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