🧬 基因注释：PRDX3

官方名称：peroxiredoxin 3

功能摘要：This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22. [provided by RefSeq, Oct 2014].

• RBFOX2 综合评分: 0.529 · 证据 2 条
• Tardbp 综合评分: 0.517 · 证据 1 条
• HNRNPC 综合评分: 0.494 · 证据 2 条
• FUS 综合评分: 0.486 · 证据 1 条
• fus 综合评分: 0.486 · 证据 1 条
• PTBP1 综合评分: 0.444 · 证据 2 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• KHSRP 综合评分: 0.398 · 证据 2 条
• ELAVL3 综合评分: 0.363 · 证据 1 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• TIA1 综合评分: 0.348 · 证据 1 条
• MBNL2 综合评分: 0.324 · 证据 1 条
• PCBP2 综合评分: 0.324 · 证据 1 条
• EWSR1 综合评分: 0.312 · 证据 2 条
• FUBP1 综合评分: 0.312 · 证据 2 条
• RBM10 综合评分: 0.312 · 证据 2 条
• HNRNPD 综合评分: 0.300 · 证据 2 条
• HNRNPK 综合评分: 0.300 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条

该基因暂无关联疾病记录