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🧬 基因注释:PSMD9

📝 官方信息

官方名称:proteasome 26S subunit, non-ATPase 9

功能摘要:The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012].

🎯 作为靶基因的剪接因子
  • RBFOX2 综合评分: 0.444 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPC 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • PRPF8 综合评分: 0.324 · 证据 1 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • Srsf1 综合评分: 0.248 · 证据 1 条
  • Tardbp 综合评分: 0.248 · 证据 1 条
  • U2af2 综合评分: 0.244 · 证据 1 条
  • AQR 综合评分: 0.212 · 证据 1 条
  • Ptbp2 综合评分: 0.200 · 证据 1 条
  • CPSF4 综合评分: 0.150 · 证据 2 条
  • CPSF6 综合评分: 0.150 · 证据 2 条
  • CPSF7 综合评分: 0.150 · 证据 2 条
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