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基因注释:PTPRR

官方信息

官方名称:protein tyrosine phosphatase receptor type R

功能摘要:The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011].

作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • FUS 综合评分: 0.362 · 证据 1 条
  • fus 综合评分: 0.362 · 证据 1 条
  • HNRNPL 综合评分: 0.300 · 证据 2 条
  • CSTF2 综合评分: 0.248 · 证据 2 条
  • Nova2 综合评分: 0.200 · 证据 1 条
  • UPF1 综合评分: 0.162 · 证据 1 条
  • CPSF6 综合评分: 0.150 · 证据 2 条
  • MSI1 综合评分: 0.150 · 证据 1 条
  • Tardbp 综合评分: 0.150 · 证据 1 条
  • CSTF2T 综合评分: 0.100 · 证据 2 条
  • Rbm7 综合评分: 0.100 · 证据 1 条
  • Rnps1 综合评分: 0.100 · 证据 1 条
  • Srsf7 综合评分: 0.100 · 证据 1 条
关联疾病

该基因暂无关联疾病记录

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