🧬 基因注释：PUM1

官方名称：pumilio RNA binding family member 1

功能摘要：This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].

• FUS 综合评分: 0.496 · 证据 1 条
• fus 综合评分: 0.496 · 证据 1 条
• HNRNPM 综合评分: 0.474 · 证据 2 条
• HNRNPC 综合评分: 0.448 · 证据 2 条
• HNRNPH1 综合评分: 0.448 · 证据 2 条
• Tardbp 综合评分: 0.444 · 证据 1 条
• HNRNPA2B1 综合评分: 0.412 · 证据 2 条
• KHSRP 综合评分: 0.398 · 证据 2 条
• HNRNPK 综合评分: 0.362 · 证据 2 条
• PTBP1 综合评分: 0.362 · 证据 2 条
• RBFOX2 综合评分: 0.362 · 证据 2 条
• HNRNPA1 综合评分: 0.350 · 证据 2 条
• HNRNPF 综合评分: 0.350 · 证据 2 条
• MBNL1 综合评分: 0.350 · 证据 2 条
• QKI 综合评分: 0.350 · 证据 1 条
• EWSR1 综合评分: 0.348 · 证据 2 条
• TIA1 综合评分: 0.312 · 证据 1 条
• HNRNPD 综合评分: 0.300 · 证据 2 条
• HNRNPL 综合评分: 0.300 · 证据 2 条
• HNRNPU 综合评分: 0.300 · 证据 2 条

该基因暂无关联疾病记录