🧬 基因注释：PFN1
📝 官方信息
官方名称：profilin 1
功能摘要：This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.638 · 证据 2 条
- RBFOX2 综合评分: 0.514 · 证据 2 条
- FUS 综合评分: 0.496 · 证据 1 条
- HNRNPL 综合评分: 0.496 · 证据 2 条
- fus 综合评分: 0.496 · 证据 1 条
- Tardbp 综合评分: 0.482 · 证据 1 条
- Srsf3 综合评分: 0.460 · 证据 1 条
- TIA1 综合评分: 0.446 · 证据 1 条
- HNRNPK 综合评分: 0.444 · 证据 2 条
- PTBP1 综合评分: 0.444 · 证据 2 条
- U2af1 综合评分: 0.413 · 证据 1 条
- HNRNPA2B1 综合评分: 0.412 · 证据 2 条
- HNRNPF 综合评分: 0.412 · 证据 2 条
- SRSF9 综合评分: 0.398 · 证据 1 条
- CELF2 综合评分: 0.379 · 证据 2 条
- ELAVL3 综合评分: 0.376 · 证据 1 条
- EWSR1 综合评分: 0.374 · 证据 2 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- HNRNPH1 综合评分: 0.350 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录