🧬 基因注释：PLA2G10
📝 官方信息
官方名称：phospholipase A2 group X
功能摘要：This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism. [provided by RefSeq, Nov 2015].
🎯 作为靶基因的剪接因子
- Ptbp2 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录