🧬 基因注释：PPIA
📝 官方信息
官方名称：peptidylprolyl isomerase A
功能摘要：This gene encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- HNRNPH1 综合评分: 0.474 · 证据 2 条
- RBFOX2 综合评分: 0.460 · 证据 2 条
- Srsf3 综合评分: 0.460 · 证据 1 条
- HNRNPC 综合评分: 0.448 · 证据 2 条
- HNRNPK 综合评分: 0.444 · 证据 2 条
- HNRNPA1 综合评分: 0.412 · 证据 2 条
- FUS 综合评分: 0.398 · 证据 1 条
- fus 综合评分: 0.398 · 证据 1 条
- EWSR1 综合评分: 0.374 · 证据 2 条
- HNRNPU 综合评分: 0.362 · 证据 2 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- CELF2 综合评分: 0.346 · 证据 2 条
- Rnps1 综合评分: 0.336 · 证据 1 条
- PRPF8 综合评分: 0.324 · 证据 1 条
- RBM15 综合评分: 0.312 · 证据 2 条
- RBM22 综合评分: 0.312 · 证据 2 条
- TIA1 综合评分: 0.312 · 证据 1 条
- Tardbp 综合评分: 0.310 · 证据 1 条
🏥 关联疾病
该基因暂无关联疾病记录