🧬 基因注释：PREX1
📝 官方信息
官方名称：phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1
功能摘要：The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008].
🎯 作为靶基因的剪接因子
- CSTF2 置信度: 2.0
- EIF4A3 置信度: 2.0
- HNRNPC 置信度: 2.0
- HNRNPK 置信度: 2.0
- HNRNPL 置信度: 2.0
- HNRNPM 置信度: 2.0
- NOVA1 置信度: 2.0
- PTBP1 置信度: 2.0
- RBFOX2 置信度: 2.0
- RBM10 置信度: 2.0
- RBM15 置信度: 2.0
- RBM39 置信度: 2.0
- CPSF2 置信度: 1.0
- ELAVL3 置信度: 1.0
- FUS 置信度: 1.0
- MBNL2 置信度: 1.0
- NXF1 置信度: 1.0
- Nova2 置信度: 1.0
- PRPF8 置信度: 1.0
- Rbm7 置信度: 1.0
🏥 关联疾病
该基因暂无关联疾病记录