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🧬 基因注释:PRMT7

📝 官方信息

官方名称:protein arginine methyltransferase 7

功能摘要:This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017].

🎯 作为靶基因的剪接因子
🏥 关联疾病
short stature-brachydactyly-obesity-global developmental delay syndrome
(0.802)
genetic disorder
(0.510)
obesity
(0.490)
brachydactyly
(0.426)
skeletal dysplasia
(0.425)
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🔗 外部数据库链接