🧬 基因注释：RHOA
📝 官方信息
官方名称：ras homolog family member A
功能摘要：This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015].
🎯 作为靶基因的剪接因子
- HNRNPC 综合评分: 0.536 · 证据 2 条
- FUS 综合评分: 0.522 · 证据 1 条
- fus 综合评分: 0.522 · 证据 1 条
- PTBP1 综合评分: 0.474 · 证据 2 条
- HNRNPA2B1 综合评分: 0.448 · 证据 2 条
- MBNL2 综合评分: 0.406 · 证据 1 条
- SRSF2 综合评分: 0.398 · 证据 1 条
- Tardbp 综合评分: 0.398 · 证据 1 条
- RBFOX2 综合评分: 0.362 · 证据 2 条
- PCBP2 综合评分: 0.360 · 证据 1 条
- HNRNPA1 综合评分: 0.350 · 证据 2 条
- HNRNPM 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- QKI 综合评分: 0.350 · 证据 1 条
- TIA1 综合评分: 0.348 · 证据 1 条
- UPF1 综合评分: 0.322 · 证据 1 条
- EWSR1 综合评分: 0.312 · 证据 2 条
- RBM15 综合评分: 0.312 · 证据 2 条
- U2af1 综合评分: 0.310 · 证据 1 条
- HNRNPD 综合评分: 0.300 · 证据 2 条
🏥 关联疾病
该基因暂无关联疾病记录