SpliceAtlasDB
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🧬 基因注释:RNPC3

📝 官方信息

官方名称:RNA binding region (RNP1, RRM) containing 3

功能摘要:Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.403 · 证据 1 条
  • PTBP1 综合评分: 0.398 · 证据 2 条
  • Srsf3 综合评分: 0.362 · 证据 1 条
  • CELF2 综合评分: 0.336 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • SRSF3 综合评分: 0.300 · 证据 1 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Rbmx 综合评分: 0.274 · 证据 1 条
  • PRPF8 综合评分: 0.262 · 证据 1 条
  • EWSR1 综合评分: 0.250 · 证据 2 条
  • FUBP1 综合评分: 0.250 · 证据 2 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM39 综合评分: 0.250 · 证据 2 条
🏥 关联疾病
isolated growth hormone deficiency, type 5
高关联 (0.717)
neurodegenerative disease
中关联 (0.526)
dentures
中关联 (0.462)
Decreased response to growth hormone stimulation test
中关联 (0.453)
isolated growth hormone deficiency type IB
中关联 (0.453)
isolated growth hormone deficiency type IA
低关联 (0.370)
atrophic gastritis
低关联 (0.275)
multinodular goiter
低关联 (0.272)
placenta praevia
低关联 (0.193)
genetic disorder
低关联 (0.193)
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