🧬 基因注释：RPS27

官方名称：ribosomal protein S27

功能摘要：Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the S27e family of ribosomal proteins and component of the 40S subunit. The encoded protein contains a C4-type zinc finger domain that can bind to zinc and may bind to nucleic acid. Mutations in this gene have been identified in numerous melanoma patients and in at least one patient with Diamond-Blackfan anemia (DBA). Elevated expression of this gene has been observed in various human cancers. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2018].

• HNRNPC 综合评分: 0.448 · 证据 2 条
• PRPF8 综合评分: 0.324 · 证据 1 条
• U2af2 综合评分: 0.314 · 证据 1 条
• U2af1 综合评分: 0.310 · 证据 1 条
• FUS 综合评分: 0.300 · 证据 1 条
• RBFOX2 综合评分: 0.300 · 证据 2 条
• SRSF9 综合评分: 0.300 · 证据 1 条
• fus 综合评分: 0.300 · 证据 1 条
• Tardbp 综合评分: 0.274 · 证据 1 条
• SF3A3 综合评分: 0.262 · 证据 1 条
• RBM10 综合评分: 0.250 · 证据 2 条
• RBM15 综合评分: 0.250 · 证据 2 条
• RBM22 综合评分: 0.250 · 证据 2 条
• TIA1 综合评分: 0.250 · 证据 1 条
• AQR 综合评分: 0.212 · 证据 1 条
• CPSF6 综合评分: 0.212 · 证据 2 条
• Srsf1 综合评分: 0.212 · 证据 1 条
• Rbmx 综合评分: 0.162 · 证据 1 条
• Rbpms 综合评分: 0.162 · 证据 1 条
• UPF1 综合评分: 0.162 · 证据 1 条

该基因暂无关联疾病记录