🧬 基因注释：RPS6
官方名称：ribosomal protein S6
功能摘要：Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].
- HNRNPC 综合评分: 0.536 · 证据 2 条
- FUS 综合评分: 0.514 · 证据 1 条
- fus 综合评分: 0.514 · 证据 1 条
- HNRNPM 综合评分: 0.474 · 证据 2 条
- Srsf3 综合评分: 0.444 · 证据 1 条
- Tardbp 综合评分: 0.430 · 证据 1 条
- PTBP1 综合评分: 0.424 · 证据 2 条
- SRSF2 综合评分: 0.424 · 证据 1 条
- SRSF9 综合评分: 0.424 · 证据 1 条
- Srsf2 综合评分: 0.362 · 证据 1 条
- HNRNPA2B1 综合评分: 0.350 · 证据 2 条
- MBNL1 综合评分: 0.350 · 证据 2 条
- EWSR1 综合评分: 0.348 · 证据 2 条
- Rnps1 综合评分: 0.336 · 证据 1 条
- U2af2 综合评分: 0.329 · 证据 1 条
- RBM10 综合评分: 0.312 · 证据 2 条
- RBM15 综合评分: 0.312 · 证据 2 条
- HNRNPL 综合评分: 0.300 · 证据 2 条
- HNRNPU 综合评分: 0.300 · 证据 2 条
- KHSRP 综合评分: 0.300 · 证据 2 条
该基因暂无关联疾病记录