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🧬 基因注释:RBMS3

📝 官方信息

官方名称:RNA binding motif single stranded interacting protein 3

功能摘要:This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].

🎯 作为靶基因的剪接因子
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • HNRNPC 综合评分: 0.412 · 证据 2 条
  • Tardbp 综合评分: 0.386 · 证据 1 条
  • HNRNPK 综合评分: 0.362 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • QKI 综合评分: 0.350 · 证据 1 条
  • NOVA1 综合评分: 0.324 · 证据 2 条
  • FUS 综合评分: 0.300 · 证据 1 条
  • HNRNPU 综合评分: 0.300 · 证据 2 条
  • KHSRP 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
  • RBFOX2 综合评分: 0.300 · 证据 2 条
  • fus 综合评分: 0.300 · 证据 1 条
  • Ptbp2 综合评分: 0.262 · 证据 1 条
  • RBM10 综合评分: 0.250 · 证据 2 条
  • RBM15 综合评分: 0.250 · 证据 2 条
  • TIA1 综合评分: 0.250 · 证据 1 条
  • Nova2 综合评分: 0.200 · 证据 1 条
  • NXF1 综合评分: 0.162 · 证据 1 条
  • ACIN1 综合评分: 0.150 · 证据 2 条
🏥 关联疾病
myopia
中关联 (0.406)
Hypermetropia
低关联 (0.399)
vitreous body disease
低关联 (0.387)
autoimmune thyroid disease
低关联 (0.356)
Abruptio Placentae
低关联 (0.336)
facial pain
低关联 (0.323)
Abnormality of refraction
低关联 (0.312)
benign prostatic hyperplasia
低关联 (0.310)
chronic obstructive pulmonary disease
低关联 (0.308)
myeloid leukemia
低关联 (0.306)
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