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🧬 基因注释:RPLP2

📝 官方信息

官方名称:ribosomal protein lateral stalk subunit P2

功能摘要:Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008].

🎯 作为靶基因的剪接因子
  • FUS 综合评分: 0.496 · 证据 1 条
  • fus 综合评分: 0.496 · 证据 1 条
  • Srsf3 综合评分: 0.460 · 证据 1 条
  • HNRNPC 综合评分: 0.448 · 证据 2 条
  • HNRNPA2B1 综合评分: 0.412 · 证据 2 条
  • QKI 综合评分: 0.412 · 证据 1 条
  • Srsf2 综合评分: 0.398 · 证据 1 条
  • RBFOX2 综合评分: 0.362 · 证据 2 条
  • SRSF9 综合评分: 0.362 · 证据 1 条
  • HNRNPA1 综合评分: 0.350 · 证据 2 条
  • HNRNPH1 综合评分: 0.350 · 证据 2 条
  • HNRNPM 综合评分: 0.350 · 证据 2 条
  • MBNL1 综合评分: 0.350 · 证据 2 条
  • Tardbp 综合评分: 0.336 · 证据 1 条
  • Rnps1 综合评分: 0.329 · 证据 1 条
  • PCBP1 综合评分: 0.324 · 证据 2 条
  • RBM15 综合评分: 0.312 · 证据 2 条
  • RBM22 综合评分: 0.312 · 证据 2 条
  • HNRNPK 综合评分: 0.300 · 证据 2 条
  • PTBP1 综合评分: 0.300 · 证据 2 条
🏥 关联疾病

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